Research Highlights:
- An evaluation of information from a long-running study of greater than 11,000 adults from 4 numerous communities within the United States has discovered that adults who had excessive blood pressure whereas each seated upright and lying supine (flat on their backs) had the next danger of coronary heart illness, stroke, coronary heart failure or untimely demise in comparison with adults with out excessive blood pressure whereas upright and supine.
- Adults who had excessive blood pressure whereas lying supine however not whereas seated upright had comparable elevated dangers of coronary heart assault, stroke, coronary heart failure or untimely demise as adults who had excessive blood pressure in each supine and upright positions.
- The elevated danger of coronary heart illness, stroke, coronary heart failure or untimely demise didn’t differ by the kind of blood pressure treatment used amongst members.
Embargoed till 6:30a.m. CT/7:30 a.m. ET Thursday, Sept. 7, 2023
BOSTON, Sept. 7, 2023 — People who had excessive blood pressure whereas lying flat on their backs had the next danger of coronary heart assault, stroke, coronary heart failure or untimely demise, in keeping with new analysis to be introduced on the American Heart Association’s Hypertension Scientific Sessions 2023, to be held Sept. 7-10, 2023, in Boston. The assembly is the premier scientific alternate centered on current advances in fundamental and medical analysis on excessive blood pressure and its relationship to cardiac and kidney illness, stroke, weight problems and genetics.
The autonomic nervous system regulates blood pressure in several physique positions; nonetheless, gravity might trigger blood to pool when seated or upright, and the physique is usually unable to correctly regulate blood pressure throughout lying, seated and standing positions, the authors famous.
“If blood pressure is only measured while people are seated upright, cardiovascular disease risk may be missed if not measured also while they are lying supine on their backs,” mentioned lead study writer Duc M. Giao, a researcher and a 4th-year M.D. pupil at Harvard Medical School in Boston.
To study physique place, blood pressure and coronary heart well being danger, the researchers examined well being knowledge for 11,369 adults from the longitudinal Atherosclerosis Risk in Communities (ARIC) study. The knowledge on supine and seated blood pressure was gathered through the enrollment interval, ARIC go to 1, which befell between 1987–1989. Participants had their blood pressure taken whereas briefly lying down at a clinic. The common age of members at the moment was 54 years previous; 56% of the group self-identified as feminine; and 25% of members self-identified as Black race. Participants on this evaluation had been adopted for a median of 25 to twenty-eight years, up by ARIC go to 5, which incorporates well being knowledge collected from 2011-2013.
The researcher’s findings included:
- 16% p.c of members who didn’t have excessive blood pressure — outlined on this study as having high and backside blood pressure measures higher than or equal to 130/80 mm Hg — whereas seated had excessive blood pressure whereas lying supine (flat on their backs), in comparison with 74% of these with seated excessive blood pressure who additionally had supine excessive blood pressure.
- In comparability to members who didn’t have excessive blood pressure whereas seated and supine, members who had excessive blood pressure whereas seated and supine had a 1.6 instances greater danger of growing coronary coronary heart illness; a 1.83 instances greater danger of growing coronary heart failure; a 1.86 instances greater danger of stroke; a 1.43 instances greater danger of general untimely demise; and a 2.18 instances greater danger of dying from coronary coronary heart illness
- Participants who had excessive blood pressure whereas supine however not whereas seated had comparable elevated dangers as members who had excessive blood pressure whereas each seated and supine.
- Differences in blood pressure treatment use didn’t have an effect on these elevated dangers in both group.
“Our findings suggest people with known risk factors for heart disease and stroke may benefit from having their blood pressure checked while lying flat on their backs,” Giao mentioned.
“Efforts to manage blood pressure during daily life may help lower blood pressure while sleeping. Future research should compare supine blood pressure measurements in the clinic with overnight measurements.”
The study’s limitations included that it centered on adults who had been middle-aged on the time of enrollment, which means the outcomes won’t be as generalizable to older populations, Giao mentioned.
Note: Giao presents Seated And Supine Blood Pressure And Risk Of Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study at 2:15 p.m. ET on Saturday, Sept. 9, 2023, Presentation #071; Abstract #452
Background:
- The Atherosclerosis Risk in Communities (ARIC) study is an ongoing, community-based cohort of 15,792 adults within the United States enrolled from 1987-1989 to research the causes for atherosclerotic illness (plaque or fatty buildup within the arteries). ARIC study members had been ages 45–65 years in the beginning of the study and from rural areas within the U.S. (Forsyth County, North Carolina, and Washington County, Maryland) and concrete areas: Minneapolis and Jackson, Mississippi. The analysis and knowledge from the ARIC medical visits — together with hospital report abstraction, ECG tracings, and doctor and coroner questionnaires, in addition to demise certificates knowledge — have led to discoveries and tips surrounding atherosclerosis, coronary heart illness, kidney illness, diabetes, stroke and cognitive decline.
- The 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults classifies hypertension as having high and backside numbers higher than or equal to 130/80 mm Hg, which was the definition of hypertension used on this study.
Co-authors and their disclosures are listed within the summary. The study was funded by the National Institutes of Health.
Statements and conclusions of research which are introduced on the American Heart Association’s scientific conferences are solely these of the study authors and don’t essentially mirror the Association’s coverage or place. The Association makes no illustration or assure as to their accuracy or reliability. The Association receives funding primarily from people; foundations and companies (together with pharmaceutical, gadget producers and different firms) additionally make donations and fund particular Association packages and occasions. The Association has strict insurance policies to stop these relationships from influencing the science content material. Revenues from pharmaceutical and biotech firms, gadget producers and medical health insurance suppliers and the Association’s general monetary data can be found right here.
Additional Resources:
- Available multimedia is on proper column of launch hyperlink https://newsroom.heart.org/news/high-blood-pressure-while-lying-down-linked-to-higher-risk-of-heart-health-complications?preview=3a007402d06b4cd7cbc3c53acb93b5f5
- Program abstracts on-line at embargo
- AHA information launch: If blood pressure rises upon standing, so might danger for coronary heart assault (March 2022)
- AHA information launch: Blood pressure rising at night time linked to doubling danger of demise in adults with diabetes (Sept. 2021)
- AHA information launch: Abnormal blood pressure ranges whereas sleeping enhance danger of coronary heart illness (November 2020)
- Follow AHA/ASA information on X (previously referred to as Twitter) @HeartNews #Hypertension23
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